DYSFUNCTIONAL BONE MARROW ENDOTHELIAL PROGENITOR CELLS ARE INVOLVED IN PATIENTS WITH MYELODYSPLASTIC SYNDROMES

Dysfunctional bone marrow endothelial progenitor cells are involved in patients with myelodysplastic syndromes

Abstract Background Myelodysplastic syndromes (MDS) are a group of heterogeneous myeloid clonal disorders characterized by ineffective haematopoiesis and immune deregulation.Emerging evidence has shown the effect of bone marrow (BM) endothelial progenitor cells (EPCs) in regulating haematopoiesis and immune balance.However, the number and functions

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Sisters with no pain, no tears: A report of a new variant of hereditary sensory and autonomic neuropathy (Type IX) Caused by a novel SCN11A mutation

Lack of pain sensation cystorelin 100ml in children involves a rare group of heritable disorders; hereditary sensory and autonomic neuropathy (HSAN).Till date, eight types of HSAN have been described depending on the clinical phenotype and the underlying gene mutation.We report a new variant of HSAN (Type IX) in two siblings (of Indian origin) with

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